 Chantix and Zyban are two non-nicotine drugs in the realm of smoking cessation aids. Though both Chantix and Zyban are available by prescription, do not contain nicotine and help in smoking cessation, there is vast difference between them. Let's find out everything about the differences between Chantix and Zyban.
Chantix pills help in smoking cessation by reducing nicotine cravings and withdrawal symptoms resulting from quitting smoking. Chantix pills work by blocking receptors in the brain linked to nicotine addiction.
Bupropion in Zyban was actually available as Wellbutrin which was an antidepressant. But later it was found Zyban had smoking cessation benefits and hence was approved as smoking cessation medicine after reports of Zyban started surfacing. The actual scientific theory behind the smoking cessation mechanism of Zyban is not yet revealed.
As said earlier, both Zyban and Chantix pills work for smoking cessation but there is a vast difference between the two medications. Here are few points of difference between Zyban and Chantix pills:
Chantix vs. Zyban
| Difference |
Chantix |
Zyban |
| Manufacturer |
Pfizer |
GlaxoSmithKline |
| Usage |
Smoking Cessation |
Smoking cessation and depression |
| Date of Approval |
European Commission: October 2006 US - FDA: May 2006 |
European Commission: June 2000 US - FDA: May 1997 |
| Treatment |
Chantix pills help i reducing nicotine cravings and withdrawal effects associated |
Mainly designed for treating a condition called major depressive disorder, Zyban was later found to have smoking cessation benefits |
| Working |
Chantix pills work by blocking the nicotinic receptors in the brain that cause addiction and help in smoking cessation |
The scientific premise behind working of Zyban is yet unknown. Its anti-depressive abilities may be the reason behind its smoking cessation benefits |
| Key Ingredient |
Varenicline Tartrate |
Bupropion Hydrochloride |
| Clinical Trials |
Chantix pills in four pivotal clinical trials which lasted for 12 weeks showed success rate of 44% in smoking cessation; in 1 year study showed 22% abstinence |
Success rate of Zyban in smoking cessation was 29.5 % and the abstinence rate was 16%. |
| Dosage |
0.5mg (white pill) and 1mg (blue pill) |
150mg twice daily |
| Contraindications |
Chantix pills are not recommended in combination with other anti-smoking drugs |
Zyban can be used in combination with nicotine replacement therapies |
It has been found in several clinical trials that Chantix pills are four times better than quitting smoking the cold turkey way and two times more effective than Zyban.
Chantix pills are way better than Zyban and this fact is clinically proven. Buy Chantix pills and increase your chances of smoking cessation.
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